Bruce D Hammock Selected Research

Burns

1/2022	sEH-derived metabolites of linoleic acid drive pathologic inflammation while impairing key innate immune cell function in burn injury.
1/2021	Plasma Linoleate Diols Are Potential Biomarkers for Severe COVID-19 Infections.
1/2021	TPPU treatment of burned mice dampens inflammation and generation of bioactive DHET which impairs neutrophil function.
12/2016	Soluble Epoxide Hydrolase Inhibition and Epoxyeicosatrienoic Acid Treatment Improve Vascularization of Engineered Skin Substitutes.

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Bruce D Hammock Research Topics

Disease

146	Inflammation (Inflammations) 02/2024 - 02/2002
59	Pain (Aches) 11/2023 - 02/2003
54	Hypertension (High Blood Pressure) 01/2021 - 02/2002
43	Neoplasms (Cancer) 02/2024 - 04/2008
21	Neuralgia (Stump Neuralgia) 01/2024 - 12/2008
17	Neuroinflammatory Diseases 06/2023 - 12/2014
17	Cardiovascular Diseases (Cardiovascular Disease) 01/2023 - 03/2002
17	Obesity 07/2021 - 08/2004
15	Carcinogenesis 02/2024 - 07/2010
15	Fibrosis (Cirrhosis) 11/2023 - 01/2012
13	Ischemia 12/2020 - 09/2004
12	Infections 03/2024 - 02/2007
11	Infarction (Infarctions) 12/2020 - 12/2007
10	Hepatocellular Carcinoma (Hepatoma) 06/2021 - 02/2002
10	Body Weight (Weight, Body) 01/2021 - 08/2004
10	Atherosclerosis 01/2017 - 02/2002
9	Chronic Pain 12/2023 - 09/2014
9	Myocardial Infarction 01/2019 - 06/2008
9	Cardiomegaly (Heart Hypertrophy) 04/2013 - 12/2006
8	Hyperalgesia 10/2022 - 11/2006
8	Seizures (Absence Seizure) 01/2020 - 05/2012
7	Arthritis (Polyarthritis) 11/2023 - 10/2013
7	Proteinuria 01/2021 - 05/2005
7	Albuminuria 01/2019 - 08/2004
7	Hypoxia (Hypoxemia) 11/2017 - 04/2006
7	Insulin Resistance 10/2017 - 02/2011
6	Neurodegenerative Diseases (Neurodegenerative Disease) 12/2023 - 06/2013
6	Cytokine Release Syndrome 07/2023 - 01/2020
6	Pancreatitis 01/2023 - 01/2014
6	COVID-19 01/2022 - 01/2020
6	Alzheimer Disease (Alzheimer's Disease) 01/2022 - 01/2018
6	Asthma (Bronchial Asthma) 01/2022 - 01/2010
6	Neoplasm Metastasis (Metastasis) 10/2021 - 01/2012
6	Stroke (Strokes) 01/2020 - 12/2005
6	Heart Failure 01/2019 - 05/2008
5	Liver Diseases (Liver Disease) 11/2023 - 12/2002
5	Sepsis (Septicemia) 01/2023 - 06/2020
5	Acute Kidney Injury (Acute Renal Failure) 01/2023 - 01/2017
5	Parkinson Disease (Parkinson's Disease) 01/2022 - 01/2018
5	Reperfusion Injury 12/2021 - 01/2010
5	Pulmonary Fibrosis (Fibrosing Alveolitis) 01/2021 - 01/2016
5	Metabolic Syndrome (Dysmetabolic Syndrome X) 01/2020 - 05/2011
5	Fatty Liver 01/2020 - 12/2003
5	Hypertrophy 01/2020 - 01/2009
4	Chronic Obstructive Pulmonary Disease (COPD) 12/2023 - 05/2012
4	Experimental Arthritis 11/2023 - 10/2013

Drug/Important Bio-Agent (IBA)

226	Epoxide HydrolasesIBA 02/2024 - 02/2002
64	AcidsIBA 03/2024 - 12/2003
54	EnzymesIBA 02/2024 - 12/2003
51	LipidsIBA 12/2023 - 01/2005
47	Fatty Acids (Saturated Fatty Acids)IBA 02/2024 - 05/2002
33	Arachidonic Acid (Vitamin F)IBA 05/2023 - 04/2004
32	Proteins (Proteins, Gene)FDA Link 02/2024 - 02/2002
30	Epoxy Compounds (Epoxides)IBA 11/2023 - 05/2002
25	Cytochrome P-450 Enzyme System (Cytochrome P450)IBA 01/2023 - 12/2003
23	OxylipinsIBA 01/2023 - 09/2006
22	Urea (Carbamide)FDA LinkGeneric 01/2022 - 02/2002
21	Unsaturated Fatty Acids (Polyunsaturated Fatty Acids)IBA 02/2024 - 05/2010
18	EicosanoidsIBA 11/2023 - 09/2007
17	Angiotensin IIIBA 01/2019 - 02/2002
15	Biomarkers (Surrogate Marker)IBA 02/2024 - 08/2009
15	LipopolysaccharidesIBA 01/2024 - 07/2005
15	CytokinesIBA 01/2023 - 05/2012
14	Analgesics (Analgesic Drugs)IBA 11/2023 - 03/2011
14	Antihypertensive Agents (Antihypertensives)IBA 10/2020 - 02/2002
13	Prostaglandin-Endoperoxide Synthases (Cyclooxygenase)IBA 01/2023 - 08/2004
12	4- (4- (3- (4- trifluoromethoxy- phenyl)ureido)cyclohexyloxy)benzoic acidIBA 07/2021 - 05/2012
12	ProstaglandinsIBA 01/2021 - 11/2006
11	Benzoic Acid (Potassium Benzoate)FDA Link 01/2018 - 08/2007
10	Linoleic Acid (Linoleate)IBA 05/2023 - 05/2010
9	Messenger RNA (mRNA)IBA 01/2021 - 12/2008
9	4- (4- (3- adamantan- 1- ylureido)cyclohexyloxy)benzoic acidIBA 04/2015 - 08/2007
8	Cyclooxygenase 2 (Cyclooxygenase-2)IBA 12/2023 - 08/2004
8	Omega-3 Fatty Acids (Omega 3 Fatty Acids)IBA 05/2023 - 07/2011
7	Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA 01/2023 - 09/2006
7	Dinoprostone (PGE2)FDA Link 10/2021 - 09/2007
7	Glucose (Dextrose)FDA LinkGeneric 01/2021 - 02/2011
6	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2021 - 08/2009
6	tetramethylenedisulfotetramine (DSTA)IBA 01/2021 - 05/2012
6	Docosahexaenoic AcidsIBA 01/2020 - 04/2013
6	Lipoxygenase (Lipoxygenase-1)IBA 01/2020 - 09/2013
6	CollagenIBA 12/2016 - 10/2013
5	SmokeIBA 12/2023 - 02/2005
5	AntigensIBA 01/2023 - 02/2007
5	Interleukin-6 (Interleukin 6)IBA 01/2021 - 07/2017
5	dual inhibitor PTUPBIBA 01/2021 - 10/2017
5	Mixed Function Oxygenases (Monooxygenases)IBA 10/2020 - 03/2011
5	Triglycerides (Triacylglycerol)IBA 09/2020 - 05/2005
5	Streptozocin (Streptozotocin)FDA Link 01/2019 - 07/2012
5	ReninIBA 12/2014 - 02/2010
5	AngiotensinsIBA 03/2014 - 05/2004
4	LeukotrienesIBA 01/2024 - 01/2020
4	AlbuminsIBA 07/2023 - 05/2005
4	Cisplatin (Platino)FDA LinkGeneric 01/2023 - 06/2009
4	CytochromesIBA 01/2023 - 04/2013
4	Opioid Analgesics (Opioids)IBA 01/2023 - 07/2012

Therapy/Procedure

39	Therapeutics 02/2024 - 02/2002
9	Oral Administration 03/2022 - 01/2009
6	Drug Therapy (Chemotherapy) 01/2023 - 11/2011
4	Immunotherapy 02/2024 - 11/2019